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Residue & Analytical Studies

Battelle can help you move your product to market quickly with GLP-compliant coordinated, customized residue and analytical studies designed to meet your regulatory compliance and global product registration needs. We offer comprehensive residue study design, management and execution, from single studies to full programs and study directorship with all studies designed to meet current European and U.S. regulations (Regulation (EC) No. 1107/2009, and US 40 CFR Part 160).


Our residue analysis experts evaluate the safety, distribution and metabolism of pesticides and other chemicals in soils and plant tissue, identifying potential concerns. 

Looking for fast, reliable results for regulatory compliance?
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We have a proven track record of conducting a wide range of study types in support of client registrations in the U.S. and Europe. Our highly experienced staff operate in modern, Good Laboratory Practice (GLP) compliant facilities to fully meet international regulatory guidelines and help you move your product to market.  We can coordinate the entire residue process and develop, adapt and validate new methodologies quickly and reliably. 


Our services include:

Residue Analysis Studies
We have extensive analytical expertise with more than 70 different active ingredients and metabolites covering all major classes of pesticides, herbicides, fungicides and biopesticides, which we can analyze in crops, soil, water, air, animal tissue and body fluids. We have the state-of-the-art facilities and technical expertise to perform highly sensitive reproducible residue analyses and adapt, develop and validate new methods as they are needed. Analytical capabilities include LC-MS/MS, UPLC, HPLC with UV, electrochemical and diode-ray detection, high resolution accurate mass (orbitrap), GC with FID, FPD, ECD and MSD.

Study Directorship
Acting as Study Director or Principle Investigator, Battelle’s analysts have extensive experience of a comprehensive range of study types, including crop residue, crop rotation, soil dissipation/accumulation, worker re-entry, pre- and post-registration method development and validation, water and air monitoring, animal feeding, ecotoxicological analysis and storage stability. We take a proactive approach to ensure excellent communication between clients and study directors to ensure that emerging issues are resolved without delay.

Field Trial Management
Battelle's team in the UK have established collaborations with European field contractors and can manage your entire European field trial process, from sourcing field contractors to sample transit and tracking, sample preparation, customized reporting and product registration support. We will plan and manage your field trials to meet international regulatory guidelines and ensure that your study meets your deadlines and requirements.

Storage Stability Studies
Battelle study directors have extensive experience managing storage stability studies in support of crop and soil residues studies. Our purpose-built facilities have continually monitored freezers set to maintain temperatures of ≤18°C.

Ecotox/Analytical Support

We have more than 10 years of experience performing analytical phases in support of ecotox studies in conjunction with "live phase" partners. Analyzing pesticide and pharmaceutical active ingredients, our state-of-the-art facilities are equipped with LC-MS/MS and HPLC systems suitable to determine the low levels of analytes from ecotox studies to derive endpoints.


Identification of Unknown Molecules
Battelle personnel have vast experience in the structure elucidation of unknown molecules derived from complex biological systems. Using an array of instrumentation (QExactive -accurate mass, LC-MS/MS QTRAP), we are capable of identifying unknowns and providing evidence-based suggestions on their structures. 

Method Development/Validation/Independent Laboratory Validation
Our study directors and analysts have extensive experience developing and validating robust methods for a variety of complex matrices (crops, soil, water, air, animal tissue and body fluids) to satisfy EU and US analytical method guidelines including:
  • SANCO 3029/99 rev 4
  • SANCO/825/00 Rev 8.1
  • OCSPP (OPPTS) 850 and 860 series guidelines
As well as validating standard multi-residue procedures for post-registration monitoring (QuEChERS, DFG S19 etc.), Battelle’s experienced analysts are capable of developing and validating compound-specific methods for pre-registration studies on a wide variety of matrices.   

Our equipment consists of:
  • Sciex 6500,5500 and 5000 LC-MS/MS systems
  • Agilent HPLC and UHPLC systems
  • Agilent GC/MS systems
  • Thermo QExactive accurate mass
  • Metrohm 850 Professional IC system with Conductivity and UV/VIS detectors
In addition, we are experienced in performing the Independent Laboratory Validation to prove robustness of the primary method. 

Battelle, via its US and UK laboratories, has the experience and capabilities to conduct both the primary Method Validation and the Independent Laboratory Validation as a package using experienced study directors at two Battelle sites.


Move your products to market quickly and confidently with coordinated, customized residue studies designed for reliable regulatory compliance and global product registrations. Battelle can coordinate the entire residue program, determine the relevant residue definition, and harmonize the Good Agricultural Practice. Battelle has extensive analytical experience adapting, developing and validating new methods quickly and reliably.

Office Locations

505 King Avenue
Columbus, OH 43201
Phone: 800-201-2011
or 614-424-6424


141 Longwater Drive, Suite 202
Norwell, MA 02061


Battelle UK Limited
29, Springfield Lyons Approach
Chelmsford Business Park
Springfield, Chelmsford
Essex, CM2 5LB, UK


Battelle UK Limited
Langstone Technology Park
Langstone Road